A Review on Hydrazone, the fascinating field of investigation in medicinal chemistry

Abstract

Antibiotic resistance is a global public health threat. There has been considerable interest in the development of novel compounds with antimicrobial, anti-mycobacterial, and antiviral activities etc. keeping Hydrazones as a centre attraction this review has been carried forward. Hydrazone possessing an azometine -NHN=CH- proton constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations have been guiding for the development of new hydrazones that possess varied biological activities. Hopefully, this will allow the development of innovative new strategies for the development of novel compounds with different scheme, methods and materials.